Researchers have demonstrated the possibility of using CRISPR/Cas9 system to cure various genetic diseases such as cancers and inherited disorders via repairing, deleting, or silencing certain genetic mutations relating to the diseases in vivo or even to clinical trials in the future.27 For example, one study revealed that CRISPR/Cas9 system could treat Duchenne muscular dystrophy via deleting exon 23 of the dystrophin gene and improving muscle function in a mouse model.[[qv: 27c]] However, there still exist some challenges when it comes to applying in clinical. The gene discussed is DMD; the disease is hereditary disease.