In an endometriosis model using Fat-1 mice, in which Omega-6 can be converted to Omega-3 PUFA, the number and weight of endometriotic lesions 2 weeks after inoculation were significantly less than in Fat-1 mice compared to controls who cannot convert Omega-6 to Omega-3 PUFA [7]. The gene discussed is FAT1; the disease is endometriosis.