PTEN and cancer: Furthermore, protein expression ofARID1A,PTEN, andPIK3CA was investigated as mutations in these genes are often prevalent in endometriosis-associated cancers and have been suggested to be involved with genomic instability and tumourigenesis (Joneset al., 2010;Kuoet al., 2009;McConechyet al., 2014;Wiegandet al., 2014;Yamamotoet al., 2012).