Whereas most participants reported that they can physically recognize if someone has HIV/AIDS, this may not be true especially in early cases of HIV infection or HIV window period or if someone has normal CD4+ cell count which can control the opportunistic infections that in most cases are responsible for signs and symptoms reported by the participants or if someone is on antiretroviral (ARVs) drugs where the HIV infection is suppressed. The gene discussed is CD4; the disease is Opportunistic infection.