Analysis of the expression of these ten prognostic genes in the ABC and GCB molecular subgroups showed that four were significantly overexpressed in the ABC subgroup: SP140 nuclear body protein (SP140) (2.3.10–19), chromodomain Y like (CDYL) (1.2.10–11), DNMT3A (2.5.10–8) and protein arginine methyltransferase 5 (PRMT5) (1.2.10–6) (Figure 2). The gene discussed is SP140; the disease is aneurysmal bone cyst.