In addition, we also examined the changes in expression of 18 genes related to tumor-infiltrating macrophages (CD163, ITGAM, MRC1, and NCAM1), myeloid cells (ARG1, CCL2, CCR2, CD68, CSF1R, CXCL8, CXCR2, and IDO1), and natural killer (NK) cells (FCGR3A, FCGR3B, KLRA1P, KLRC1, KLRD1, and NCR1) in subgroups divided by the Th1 score, the Th2 score, and a combination of the two, compared with the median expression of each gene (Supplementary Figure 6A). This evidence concerns the gene CXCL8 and neoplasm.