Additionally, DSF did not upregulate MICA expression in normal human hepatocytes, with very low protein levels of MICA and ADAM10 in contrast to HCC cells [8, 17, 18], or interfere with NKG2D expression in NK cells (Figure 3A and 3B), which indicated selective enhancement of mMICA levels in HCC cells and efficient transduction of signaling for NK cell activation. Here, MICA is linked to hepatocellular carcinoma.