Consistently with previously published data [9], while the cell lines harboring wild type LKB1 in the NSCLC panel (HOP-62, H1299 and H441) showed a clear reduction in MYC levels, the cell lines with the mutated tumor suppressor (A549, H460 and H23) did not show a comparable regulation. The gene discussed is STK11; the disease is non-small cell lung carcinoma.