To determine the potential regulation of MYC in murine PDAC and NSCLC tumors treated with BAY 1238097, we generated two cell lines from each tumor type (PDAC: mPDAC 1.1 and mPDAC 1.2; NSCLC: MLT#1 and MLT#6) (Supplementary Figure 3) and treated them in vitro for 3 days with the compound. Here, MYC is linked to neoplasm.