Other serum biomarkers reported in low case numbers of urachal adenocarcinomas include lactate dehydrogenase (LDH) [80, 199], cancer antigen 15-3 (CA15-3) [26, 114, 156], AFP [16, 42, 95, 106, 156] with one case in a seven-month-old infant with a yolk sac tumor of the urachus [295], and neuron-specific enolase (NSE) [156] including one case of a neuroblastoma in a six-month-old child [296]. This evidence concerns the gene ENO2 and cancer.