Compared to nT2DM patients without MetS, nT2DM patients with MetS had higher levels of BMI, BF%, SBP, DBP, TC, TG, apoB, FPG, 2hPG, ALT, GGT, WBC count, hs-CRP, FIns, HOMA-IR, apoB/apoA, and TyG index (P < 0.001 or P < 0.01 or P < 0.05) and lower levels of HDL-C, apoA, and lymphocyte count (P < 0.001 or P < 0.05). The gene discussed is CRP; the disease is metabolic syndrome.