The overexpression of CCNG2 caused a significantly higher fraction of glioma cells in the G0/G1 phase (56.9% in U251 cells and 33.5% in T98G cells) than in the non-transfected cells (33.9% in U251 cells and 17.6% in T98G cells), whereas cells in S phase were reduced by around 50%, suggesting that CCNG2 expression might induce a G0/G1 phase arrest in U251 and T98G cells. The gene discussed is CCNG2; the disease is glioma.