GPR158 and neoplasm: Of translational importance, miR-449a expression correlates with tumour grade (Fig. 7c) and with poorer survival (p = 0.004, Fig. 8a), and consistent with our experimental data, GPR158 expression correlates with better prognosis (Figs. 8b-i) and inversely with tumour grade (Figs. 7e, i, h and 9b).