Expression of the voltage-gated potassium channels KCNU1, KCNQ3 and KCNAB2 was increased in highly metastatic lines, whereas SCNN1A, encoding the alpha subunit of the major epithelial sodium channel (non-voltage-gated) and regulated by glucocorticoids (Fietz et al., 2017), was downregulated in all three metastatic tumours and is a candidate metastasis suppressor gene (Table 2). The gene discussed is ENSG00000280371; the disease is neoplasm.