Rett syndrome (RTT) is a neurological disorder that almost exclusively affects females with an incidence of 1:10,000 live births [15] due to a loss-of-function mutations of the X-linked methyl-CpG binding protein 2 (MeCP2) gene in approximately 90% of classic RTT cases [16]. This evidence concerns the gene MECP2 and atypical Rett syndrome.