CD8A and hepatocellular carcinoma: From the 183 HCC serial sections for VISTA and CD8 + TILs IHC analysis, we classified 4 immune subtypes: VISTA+/CD8+ (16.9%, 31/183), VISTA+/CD8- (12.6%, 23/183), VISTA-/CD8+ (16.4%, 30/183), and VISTA-/CD8+ (54.1%, 99/183) (Fig. 3a).