BHLHA15 and familial pancreatic carcinoma: Importantly, these data suggest that MIST1 can access target gene promoters in pancreatic cancer cells despite the inherent mutations, genomic instability, and altered epigenetic marks that are associated with these transformed cells (Deer et al., 2010; Fazio et al., 2017; Mehmood et al., 2014; Pin et al., 2015; Tan et al., 2009).