The enriched genes from this pathway contained a number of genes implicated as prognostic markers in oesophageal and other cancers, such as Insulin-like Growth Factor Binding Protein 1 (IGFBP1), N-myc Downstream Regulated Gene 1 (NDRG1), Trefoil Factor 3 (TFF3) and Solute Carrier Family 2 Member 1/Glucose Transporter 1 (SLC2A1). The gene discussed is IGFBPL1; the disease is cancer.