CCN2 and familial pancreatic carcinoma: Based on previous pancreatic cancer studies using FG-3019 [22, 23, 25], we chose the cell lines which expressed higher CTGF levels; ACC-MESO-4 (epithelioid type) with high expression, and Y-MESO-8D (sarcomatoid type) and NCI-H290 (epithelioid type), with moderate to low expression.