The TRPV2 interactome showed a high association with early glia-related neoplasms, especially glioma/glioblastoma, being ABR, FGF1, KCNJ10, PEBP1, PLP1, SDC3, and TRPV2, the genes associated to these brain neoplasms. The gene discussed is PLP1; the disease is neoplasm.