EMSA and supershift analysis furthermore revealed, that the increase in cytoplasmic HuR abundance is concomitant with an increase in RNA binding of drug-inducible complexes (C2, C3 and C4) to the 3ʹUTR of human cyclooxygenase-2 (COX-2) (Supplementary Figure 6), a prototypical HuR target in colon carcinoma cells [25]. Here, ELAVL1 is linked to colon carcinoma.