Our previous study has demonstrated that β3GnT8 is able to promote the metastasis of colorectal cancer by catalyzing the elongation of β1,6-branched polylactosamines of cluster of differentiation 147 (CD147), a transmembrane glycoprotein mediating tumor invasion and metastasis [8, 9]. The gene discussed is B3GNT8; the disease is colorectal cancer.