JUN and hepatocellular carcinoma: As shown in Figure 8B and 8C, knockdown of c-Jun by si-c-Jun markedly suppressed β3GnT8-induced expression of HG-CD147 and polylactosamines as well as HCC cell invasion and migration by blocking β3GnT8 expression, indicating that expression and function of β3GnT8 are dependent on c-Jun.