EGFR and head and neck squamous cell carcinoma: In addition to tyrosine kinase inhibitors (TKIs), Cetuximab (and other antibodies) is approved for HNSCC (together with radiotherapy; including recurrent or metastatic head and neck cancer) as well as KRAS wild-type and EGFR-expressing metastatic colorectal cancer (https://clinicaltrials.gov/).