CSF1R and familial pancreatic carcinoma: In order to gain deeper insight into the role of macrophages in pancreatic cancer, we investigated the therapeutic impact of inhibiting myeloid cell recruitment using AZD7507 (Scott et al., 2013), a small-molecule tight binding ATP-competitive inhibitor of CSF1R signaling, the structure of which is available at https://pubchem.ncbi.nlm.nih.gov/compound/25001557.