FN1 and fibrosis: Fn1 expression was increased by 2.2 fold in the skin (Fig 3A) and by 4.8 fold in the lungs (Fig 3B) of tamoxifen-injected mice whereas the fibrosis-associated splice variant Fn-Eda displayed 5.5 fold and 2.5 fold increased expression in the skin and lung, respectively, compared to control animals.