CYP2R1 and diabetes mellitus: In CKB, none of the individual variants were significantly associated with risk of diabetes (n = 5,566), with per allele adjusted ORs (95% CIs) of 0.97 (0.93–1.01) for DHCR7-rs12785878, 1.00 (0.96–1.04) for CYP2R1-rs10741657, 1.00 (0.95–1.05) for CYP24A1-rs6013897, and 1.01 (0.96–1.05) for GC/DBP-rs2282679 (S6 Fig).