AKAP-12 protein levels inversely correlated with serum Aldo (r = −0.4624, p < 0.05; Fig. 6A) in AS patients and positively correlated with PGC-1α mRNA levels (r = 0.5784, p < 0.01; Fig. 6B) in the whole population. Here, AKAP12 is linked to aortic stenosis.