There was no significant difference for AMD variants including rs1061170 (His402Tyr) and rs800292 (Val62Ile) in CFH, rs10490924 (Ala69Ser) in ARMS2. The variant rs2230199 (Arg102Gly) in C3 was significantly most frequent in EMAP patients (Table 3). This evidence concerns the gene C3 and age-related macular degeneration.