STAT3 and renal cell carcinoma: In addition, the expression of G3BP1 is positively correlated with IL-6 (r = 0.510, p = 0.003) and p-STAT3 (r = 0.683, p < 0.0001) in RCC tissues (Table 2), suggesting the associations of IL-6/G3BP1/STAT3 molecules in primary RCC.