Studies on mice have been conducted to dissect the involvement of MBNL1 and CELF1 in DM1 (Timchenko et al., 2004; Ho et al., 2005; Kanadia et al., 2006; Wang et al., 2007; Koshelev et al., 2010; Ward et al., 2010; Suenaga et al., 2012). The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.