MUC16 and cystadenoma: Notably, both ovarian endometriotic cysts and cystadenoma have odds of developing into endometrioid cancer (or clear cell cancer; incidence rate: 0.2–0.8%) [6] or cystadenocarcinoma (primarily serous carcinoma; incidence rate: 0.4–0.6%) [7], which complicates the clinical settings for early diagnosis and places more obstacles on the TVU and CA125-based screening programs.