Therefore, the aim of this study was to profile the characteristic patterns of postprandial fluctuations of CA125 in the peripheral blood associated with endometriosis and benign and malignant epithelial tumors of the ovary and to assess the applicability of utilizing postprandial increases in serum CA125 to detect early-stage ovarian cancer in a complex pathological condition. Here, MUC16 is linked to ovarian cancer.