In 98 GI and pancreatic NETs, the sensitivity and 95% confidence interval (95% CI) for NKX2.2, PDX-1, and CDX-2 were 84% (95% CI, 75% - 90%), 14% (95% CI, 8% - 23%), and 53% (95% CI, 43% - 63%), respectively. This evidence concerns the gene CDX2 and pancreatic neuroendocrine tumor.