ACE and type 2 diabetes mellitus: Similarly, RAAS activation is associated with the presence of insulin resistance and the development of T2D, with angiotensin‐converting enzyme (ACE) inhibitors shown to lessen important hallmarks of diabetic cardiomyopathy, such as oxidative damage, inflammation, cardiomyocyte hypertrophy and apoptosis, and myocardial fibrosis.107, 108