Levels of TNF-α were elevated in patients with SJS/TEN during the acute stage (3.33 [2.80] pg/ml) compared with the resolution stage (2.53 ± 0.81 pg/ml; P = 0.012) or normal individuals (1.93 ± 0.49 pg/ml; P < 0.001; Fig. 2). The gene discussed is TNF; the disease is toxic epidermal necrolysis.