The expression of Fas receptor and FasL is relatively high in the cells of the immune system, which mediates apoptosis/proliferation plays an important role in asthma T cells with dysregulation of apoptosis/proliferation, Th1/Th2 imbalance, airway inflammation, airway hyperresponsiveness (AHR) and airway remodeling. The gene discussed is FASLG; the disease is airway hyperresponsiveness.