FGFR2 and LADD syndrome: Lacrimo-auriculo-dento-digital (LADD; Online Mendelian Inheritance in Man (OMIM) database no. 149730) syndrome, a congenital autosomal dominant disorder, results from the heterozygous missense mutations in FGF10, FGFR2, and FGFR3. LADD is characterized by aplasia, hypoplasia/atresia of salivary/lacrimal glands, ears with cup shape, and hearing loss [145–148], as well as various dental phenotypes, including hypodontia, teeth with peg shape, and hypoplastic enamel [149].