Similar to KCa1.1-expressing prostate cancer cells (Yan and Aldrich, 2010), LRRC26 was the main auxiliary subunit of KCa1.1 in KCa1.1-expressing breast cancer MDA-MB-453 cells (Figure 5A, vehicle) and breast cancer tissues (Supplementary Figure S3C). The gene discussed is KCNMA1; the disease is prostate cancer.