AR and Familial prostate cancer: Östling et al. (2011) identified 71 unique miRNAs that influenced AR levels in prostate cancer cells (Östling et al., 2011), and previous studies identified several KCa1.1-down-regulating miRNAs (Östling et al., 2011; Tatro et al., 2013; Kroiss et al., 2015; Cheng et al., 2016; Samuel et al., 2016; Lu et al., 2017).