MAPK7 and cancer: Ingenuity pathway analysis (IPA) of the differentially expressed genes revealed high enrichment in cancer-associated pathways and predicted suppression of DNA damage repair (DDR) and extracellular signal-regulated kinase 5 (ERK5) signaling (Fig. 4e, Supplementary Figure 14, and Supplementary Data 5), both of which are critical for cisplatin resistance1.