Furthermore, LY3300054 therapy resulted in prominent immune-related gene expression changes consistent with IFNγ pathway and T cell activation in the tumor tissue (Fig. 6e), as well as in spleen (Additional file 1: Figure S7A) and peripheral blood cells (Additional file 1: Figure S7B), and to a much lesser extent in the bone marrow (Additional file 1: Figure S7C). The gene discussed is IFNG; the disease is neoplasm.