According to multivariate regression analysis including CEI, indirect bilirubin, and serum albumin, the CEI was a significant and independent pretreatment predictor associated with developing hyperbilirubinemia (odds ratio 9.08, p = 0.046, 95% CI: 1.05–78.86) with Akaike’s Information Criterion of 33.67 and AUROC of 0.739 (Table 5). This evidence concerns the gene ALB and Hyperbilirubinemia.