Regarding immunodiagnostic of TB, interferon gamma released assays (IGRA) has improved the identification of asymptomatic latent TB (LTB) in low incidence countries [3–4] but were unable to distinguish active from latent TB infection [5–7], and commercial assays based on antibody detection failed to reach the expected performances for a diagnosis assay dedicated to TB diagnosis [8]. Here, IFNG is linked to tuberculosis.