The most suppressed genes in CDD included lipid synthesis genes (Sqle,Elovl3,Elovl6,Aacs,Acly,Acss2,Acacb), the endopeptidase inhibitorSerpina4-ps1 and the multifunctional triglyceride metabolism enzymePnpla3. This evidence concerns the gene ELOVL3 and craniodiaphyseal dysplasia.