TSLP and asthma: Buchheitet al. report that in aspirin exacerbated respiratory disease (AERD), a subtype of CRS/asthma which manifests with recurrent polyposis, CRS, asthma, and non-steroidal anti-inflammatory drug (NSAID) sensitivity, TSLP also drove prostaglandin D2 (PGD2) production from mast cells and was increased in active form in local polyp tissue, thus contributing to the inflammatory cascade10.