The result suggested the presence of a positive correlation between CNPY2 and AR target genes expression levels (KLK3: r = 0.5190, TMPRSS2: r = 0.5307) in these prostate cancer patient samples (Figure 5B), indicating that CNPY2 expression was positively correlated with AR expression and AR transcriptional activation in prostate cancer patients. Here, TMPRSS2 is linked to Familial prostate cancer.