We generated reporter lines expressing three previously cloned human TCRs specific for peptides derived from the tumor antigens PRAME (SLLQHLIGL; HLA-A*02:01 restricted; [18]) and BOB1/p44 (APAPTAVVL; HLA-B*07:02 restricted; [19]) and to a well-characterized virus antigen CMV pp65 peptide (NLVPMVATV; HLA-A*02:01 restricted; [17]). Here, HLA-B is linked to neoplasm.