In contrast, the frequency of IFNγ-secreting cells trended to be uniformly yet non-significantly lower in SSc (28.4 ± 6.97 vs 48.96 ± 9.05, p < 0.09, 47.8 ± 11.37 vs 75.9 ± 2.34, p < 0.083, 40.4 ± 9.62 vs 71.9 ± 9.68, p < 0.058). The gene discussed is IFNG; the disease is systemic sclerosis.