In conclusion, TQ treatment caused a decrease in the level of Cyto-c, Casp-3, LDH, and Aβ-42 in brain homogenates, thus proving to be a good choice for restoring memory and cognitive deficits induced by Glu-excitotoxicity, as reflected by improvements in SAB%, MEL, and time spent in the target quadrant. The gene discussed is CASP3; the disease is Cognitive impairment.