In addition, CD44v6 and CD44v10 splice variants were significantly higher in AD hippocampal neurons (Pinner et al., 2017), and in lung fibrosis, CD44v6 is mediating the induction of COL1 pro-fibrotic action of TGFβ1 (Ghatak et al., 2014). The gene discussed is TGFB1; the disease is Alzheimer disease.