OLR1 and coronary artery disorder: Finally, LOX-1 is believed to be a predictor of coronary heart diseases and cardiovascular events.[32] In stable coronary artery disease, patients with lesions of the proximal/middle segment of left anterior descending (LAD) coronary artery have significantly higher circulating soluble LOX-1 levels than patients with lesions in the distal segments of the LAD; thus, LOX-1 levels are associated with the proximal/middle segment of LAD lesions.[33]