In contrast to the heart, progerin mRNA isolated from whole mononuclear blood cells of DCM patients (n = 56) or healthy controls (n = 10) did not reveal significantly different progerin levels as revealed by unpaired T-Test analysis (0.75 ± 0.60 vs. 0.83 ± 0.24; p = 0.661 between the groups; Fig 3B). The gene discussed is LMNA; the disease is familial dilated cardiomyopathy.