Since LMNA gene mutations are causally involved in patients with idiopathic dilated cardiomyopathy (3.6%) and familial dilated cardiomyopathy (7.5%) [27], we hypothesized that accumulation of progerin in non HGPS ́s individuals in the heart may as well be involved in the progression of DCM. This evidence concerns the gene LMNA and idiopathic dilated cardiomyopathy.