HLA-C and nemaline myopathy: Analysis of myofibril and sarcomere morphology by staining for actin and Myosin heavy chain (Mhc) showed that all sqh and zip knock-down fibers contain prominent actin accumulations (Fig 5B, 5D, 5F, 5H, 5J and 5L), which are often a landmark of nemaline myopathies [27,28].